Certified Pediatric Hematology Oncology Nurse (CPHON) Practice Exam 2026 - Free CPHON Practice Questions and Study Guide

The estimated incidence of Schwachman-Diamond Syndrome is approximately 1 in 20,000 births. This genetic disorder primarily affects the pancreas, bone marrow, and skeleton, leading to symptoms such as pancreatic insufficiency, recurrent infections due to bone marrow dysfunction, and skeletal abnormalities. The specific incidence is based on available epidemiological studies that analyze the prevalence of this rare condition.

While the other options provide different incidence figures, they do not accurately reflect the established estimates from current medical literature, which consistently supports the 1 in 20,000 births figure. This understanding is crucial for healthcare professionals, as recognizing the incidence can aid in early detection and management of the syndrome in affected individuals.