Certified Pediatric Hematology Oncology Nurse (CPHON) Practice Exam 2025 - Free CPHON Practice Questions and Study Guide

Schwachman-Diamond Syndrome is primarily characterized by defects in both B and T lymphocytes, which are crucial components of the adaptive immune system. These lymphocytes are responsible for orchestrating immune responses, with B cells producing antibodies and T cells playing a vital role in cell-mediated immunity. The defective functioning of these immune cells in Schwachman-Diamond Syndrome leads to a weakened immune response, making individuals more susceptible to infections.

In this context, the other cell types mentioned do not represent the core issues associated with Schwachman-Diamond Syndrome. Red blood cells are primarily related to oxygen transport in the body, while platelets are involved in blood clotting. Neutrophils, as part of the innate immune system, are also important, but the key characteristics of Schwachman-Diamond Syndrome specifically relate to the impairment of immune functions linked to B and T lymphocytes. Therefore, understanding the involvement of these adaptive immune cells is crucial for comprehending the pathology and clinical implications of the syndrome.