Certified Pediatric Hematology Oncology Nurse (CPHON) Practice Exam 2025 - Free CPHON Practice Questions and Study Guide

Fanconi Anemia is a genetic disorder characterized by specific clinical features, many of which are well-defined. Among these classic symptoms, macrocytic anemia, short stature, and eye and eyelid abnormalities are commonly observed.

Macrocytic anemia results from the bone marrow's inability to produce adequate blood cells, which is a hallmark of Fanconi Anemia. Short stature is often noted due to the impact of the disorder on growth and development. Eye and eyelid abnormalities can manifest in various forms, including disturbances in the structure and function of these areas.

In contrast, late-onset deafness is not classically associated with Fanconi Anemia. While the disorder can lead to a range of complications, auditory dysfunction is not a typical or classic symptom recognized within the core manifestations of Fanconi Anemia. This distinction highlights the unique set of symptoms that characterize this condition and underscores the importance of understanding the specifics of genetic disorders in pediatric hematology.